| Gene name: | AGT |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | Aorta |
| Cell name: | VSMC |
| Gene ID: | 183 |
| Category: | protein coding |
| Phenotype: | Atherosclerosis |
| Experimental category: | L |
| PMID: | 16908765 |
| Experiment: | SA-β-gal activity assay |
| Description: | SA β-gal activity was significantly increased in Ang II–treated VSMCs compared with control cells.Consistent with our in vitro data, treatment with Ang II enhanced SA β-gal activity in the aortas of apoE-deficient mice. |
| Regulatory pathway: | P53-P21 |
| R-AG-Pathway: | Upregulation |
| Official symbol(s): | TP53-CDKN1A |
| Pathway experiment: | Western blot |
| Pathway description: | Moreover, expression of p21 and p53 was elevated in Ang II–treated VSMCs. |
Annotation:
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