Aging Overview

Aging gene

Gene name: TERT
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: GBM
Gene ID: 7015
Category: protein coding
Phenotype: Ataxia telangiectasia
Experimental category: L
PMID: 14570874
Experiment: SA-β-gal activity assay//BrdU assay//TRF assay//Cell counting
Description: The TRF assay showed that the telomere length of AT/TERT cells was extended to >12 kb, compared with ~4–11 kb for parental AT cells.Whereas parental AT cells underwent replicative senescence after ~24 PDs, AT/TERT cells survived for >70 to 100 PDs.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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