| Gene name: | MYC |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | Liver,Lymphoma |
| Cell name: | -- |
| Experiment: | SA-β-gal activity assay |
| Description: | The suppression of MYC in primary MYC-induced lymphoma and hepatocellular carcinoma resulted in senescence-associated acidic β-gal (SA-β-Gal) staining. |
| Target gene: | P15INK4B//P21CIP |
| Official symbol(s): | P15INK4B//P21CIP |
| R-AG-Target gene: | --//-- |
| Subcategory: | Unclear |
| Target gene experiment: | qRT-PCR |
| Target gene description: | Among them, p15INK4b and p21CIP have been shown to be MYC targets.Upon MYC inactivation in vitro,osteosarcoma cell lines exhibited the induction of p15INK4b and p21CIP mRNA expression by quantitative RT-PCR. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
Loading,please wait...