Aging Overview

Aging gene

Gene name: SLC16A7
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: LoVo,HT29,HCT-8,HCT116,SW480 ,MKN45,MKN74
Gene ID: 9194
Category: protein coding
Phenotype: Colorectal cancer
Experimental category: L
PMID: 22964484
Experiment: SA-β-gal activity assay//Cell morphological analysis//Immunostaining//SAHF
Description: All the cancer cell lines examined, including those of the colon (HCT8, HCT116, HT29, LoVo, and SW480) and stomach (MKN45 and MKN74), displayed cellular enlargement and flattening as well as positivity for SA-β-Gal staining, following knockdown of MCT2. Cells additionally exhibited senescence-associated nuclear properties,including elevation of PML bodies, gH2AX, and SAHF.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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