Gene name: | SLC16A7 |
Aging type: | Prevent |
Aging characteristic: |
Tissue type: | -- |
Cell name: | LoVo,HT29,HCT-8,HCT116,SW480 ,MKN45,MKN74 |
Gene ID: | 9194 |
Category: | protein coding |
Phenotype: | Colorectal cancer |
Experimental category: | L |
PMID: | 22964484 |
Experiment: | SA-β-gal activity assay//Cell morphological analysis//Immunostaining//SAHF |
Description: | All the cancer cell lines examined, including those of the colon (HCT8, HCT116, HT29, LoVo, and SW480) and stomach (MKN45 and MKN74), displayed cellular enlargement and flattening as well as positivity for SA-β-Gal staining, following knockdown of MCT2. Cells additionally exhibited senescence-associated nuclear properties,including elevation of PML bodies, gH2AX, and SAHF. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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