| Gene name: | USP10 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | IMR-90,HFF |
| Experiment: | SA-β-gal activity assay//Western blot |
| Description: | USP10 overexpression stabilized p14ARF protein levels in both cell lines.In line with these observations, these cells exhibited accelerated cellular senescence with decreased cellular growth. These phenomena were prevented by p14ARF ablation under USP10 overexpression. Overall, these results indicated that USP10 could accelerate cellular senescence through p14ARF stabilization. |
| Target gene: | P14 |
| Official symbol(s): | P14 |
| R-AG-Target gene: | -- |
| Subcategory: | Unclear |
| Target gene experiment: | Western blot |
| Target gene description: | USP10 overexpression stabilized p14ARF protein levels in both cell lines. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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