| Gene name: | PRKAA1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | HUVEC |
| Gene ID: | 5562 |
| Category: | protein coding |
| Phenotype: | Diabetic vascular complication |
| Experimental category: | L |
| PMID: | 26629991 |
| Experiment: | SA-β-gal activity assay//Western blot |
| Description: | It was shown that silencing of AMPK expression diminished SIRT1 activation and its downstream signaling.Moreover, it abolished the protective effects of RSV and MET against enhanced oxidative stress and accelerated cellular aging. |
| Target gene: | SIRT1 |
| Official symbol(s): | SIRT1 |
| R-AG-Target gene: | -- |
| Subcategory: | Unclear |
| Target gene experiment: | Western blot |
| Target gene description: | It was shown that silencing of AMPK expression diminished SIRT1 activation and its downstream signaling. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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