| Gene name: | SIRT1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | Plaques and normal vessel |
| Cell name: | VSMC |
| Gene ID: | 23411 |
| Category: | protein coding |
| Phenotype: | Atherosclerosis |
| Experimental category: | L |
| PMID: | 23224247 |
| Experiment: | qPCR//Western blot |
| Description: | SIRT1 mRNA was significantly decreased in the media of plaques versus normal vessels, associated with significantly increased p16ink4.SIRT1 mRNA and protein expression were reduced in plaque VSMCs and senescent aortic VSMCs versus early-passage normal human VSMCs. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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