Aging Overview

Aging gene

Gene name: BMI1
Aging type: Prevent
Aging characteristic:
Tissue type: Kidney
Cell name: Renal cell
Gene ID: 648
Category: protein coding
Phenotype: Renal tubulointerstitial injury
Experimental category: HL
PMID: 28790310
Experiment: Immunostaining//TUNEL assay//SA-β-gal activity assay
Description: Results showed that the percentage of Ki67-positive cells was decreased dramatically, whereas the percentage of TUNEL-positive cells, SA-β-gal positive areas, 8-OHdG-positive cells, CD3-positive and F4/80-positive inflammatory cells were significantly increased in Bmi-1-/-mice compared with WT mice.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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