Gene name: | SRC |
Aging type: | Accelerate |
Aging characteristic: |
Tissue type: | -- |
Cell name: | Human endothelial cell |
Experiment: | SA-β-gal activity assay |
Description: | Incubation with H2O2 significantly increased acidic β-galac-tosidase–positive cells. Interestingly, coincubation with the Src kinase inhibitor PP2 (500 nmol/L) completely blocked the induction of premature senescence indicating that Src kinase activation contributes to endothelial cell senescence. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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