Aging Overview

Aging gene

Gene name: SRC
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: Human endothelial cell
Gene ID: 6714
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 14963003
Experiment: SA-β-gal activity assay
Description: Incubation with H2O2 significantly increased acidic β-galac-tosidase–positive cells. Interestingly, coincubation with the Src kinase inhibitor PP2 (500 nmol/L) completely blocked the induction of premature senescence indicating that Src kinase activation contributes to endothelial cell senescence.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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