| Gene name: | PIK3CA |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | BJ-T |
| Experiment: | SA-β-gal activity assay//Cell morphological analysis |
| Description: | Cells expressing PIK3CAE545K exhibited a significant increase in cell size and senescence associated β-galactosidase activity (SAβGAL). |
| Regulatory pathway: | PI3K-AKT |
| R-AG-Pathway: | Activation |
| Official symbol(s): | PIK3CA-AKT1 |
| Pathway experiment: | Western blot |
| Pathway description: | Cells with expressing PIK3CAE545K exhibited increased levels of phospho-AKT and phosphorylation of the AKT substrate PRAS40. |
Annotation:
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