Aging Overview

Aging gene

Gene name: CDKN1A
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: MCF-7
Gene ID: 1026
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 19648966
Experiment: Cell morphological analysis//Flow cytometry
Description: Microscopic analysis revealed that control cells formed a stably proliferating population, whereas cells transfected with the cdk inhibitors, p21 stopped proliferation and adopted a senescent morphology. Flow cytometry data confirmed proliferation of control cells and induction of a G1-phase arrest in cells expressing exogenous p21.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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