Aging Overview

Aging gene

Gene name: PRKDC
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: Fibroblast
Gene ID: 5591
Category: protein coding
Phenotype: Idiopathic Pulmonary Fibrosis
Experimental category: L
PMID: 31464599
Experiment: qRT-PCR
Description: Transcriptomic analysis of Nu7441(DNA-PKcs inhibitor)-treated and untreated fibroblasts showed that this treatment caused a significant increase in the senescence-associated CDKN1A, CDKN1B, CDKN2A, NOX4.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

Loading,please wait...