| Gene name: | SKP2 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | MDA-MB-231,BT-549 |
| Experiment: | SA-β-gal activity assay |
| Description: | Staining for β-Galactosidase shows that induction of SKP2 partially suppressed the emergence of ?-Gal-positive senescent cells by 50% following SETD1A-KD. |
| Target gene: | P21//P27 |
| Official symbol(s): | P21//P27 |
| R-AG-Target gene: | Downregulation//Downregulation |
| Subcategory: | Methylation |
| Target gene experiment: | Western blot |
| Target gene description: | Inducible expression of SKP2 in SETD1A-KD cells(using two different shSET1A constructs) effectively reduced the expression of p27 and p21 proteins. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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