Aging Overview

Aging gene

Gene name: LMNA
Aging type: Accelerate
Aging characteristic:
Tissue type: Skin
Cell name: Primary dermal Fibroblast
Gene ID: 4000
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 18363904
Experiment: SA-β-gal activity assay
Description: These analyses demonstrate that cells expressing progerin display a progressive, passage-dependent increase in the percentage of senescent cells over a time frame which spanned passages 5–10 compared to control cells ,which levels off after passage 10.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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