| Gene name: | NAMPT |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | Aortas |
| Cell name: | -- |
| Gene ID: | 10135 |
| Category: | protein coding |
| Phenotype: | Human Thoracic Aortic Aneurysm Disease |
| Experimental category: | L |
| PMID: | 28356339 |
| Experiment: | SA-β-gal activity assay |
| Description: | However, in SMC-Nampt deficient mice there was SA-β-gal activity throughout the ascending aorta, arch,and proximal descending thoracic aorta after 7 days of Ang II infusion. |
| Target gene: | P16 |
| Official symbol(s): | P16 |
| R-AG-Target gene: | -- |
| Subcategory: | Unclear |
| Target gene experiment: | Western blot |
| Target gene description: | This revealed a 6.1-fold increase in the abundance of p16-expressing cells in the media of the ascending aorta of Ang II-infused SMC-Nampt KO mice relative to Ang II-infused control mice and a 4.7-fold increase in the thoracic aorta. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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