| Gene name: | SUV39H1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | BEL-7402,SMMC-7721,MHCC97L,HuH-7 |
| Gene ID: | 6839 |
| Category: | protein coding |
| Phenotype: | Hepatocellular carcinoma |
| Experimental category: | L |
| PMID: | 22991213 |
| Experiment: | Colony formation assay//Cell proliferation assay//SA-β-gal activity assay//Knockdown |
| Description: | We showed that overexpression of SUV39H1 remarkably enhanced HCC cell clonogenicity, whereas SUV39H1 knockdown HCC cells reduced colony-forming ability;Knockdown of SUV39H1 significantly decreased cell proliferation and anchorage-independent growth of HCC cells;We observed an elevated senescence-associated lysosomal β-Gal activity in SUV39H1 knockdown cells. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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