Aging Overview

Aging gene

Gene name: HSF1
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: MCF 10A
Gene ID: 3297
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 20622894
Experiment: Growth curve assay//Cell morphological analysis
Description: When we expressed HER2 in HSF1-depleted cells, a significant growth inhibition was observed, associated with a significant change in cells’ appearance, including enlarged, flattened morphology and extensive vacuolization reminiscent of senescence.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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