Gene name: | TERT |
Aging type: | Prevent |
Aging characteristic: |
Tissue type: | Lung |
Cell name: | -- |
Gene ID: | 7015 |
Category: | protein coding |
Phenotype: | Inflammation |
Experimental category: | L |
PMID: | 26518879 |
Experiment: | SA-β-gal activity assay//Immunostaining |
Description: | β-Gal staining for cellular senescence was markedly increased in G3 TERT-null lung sections compared with control.We analyzed the levels of heterochromatin protein 1γ(HP1γ), a marker for senescence-associated heterochromatin foci, and found that immunoreActivate HP1γ was also markedly increased, with the level of HP1γin G3 TERT-/- being more than 2.5 times that in WT control animals. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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