Aging Overview

Aging gene

Gene name: TERT
Aging type: Prevent
Aging characteristic:
Tissue type: Lung
Cell name: --
Gene ID: 7015
Category: protein coding
Phenotype: Inflammation
Experimental category: L
PMID: 26518879
Experiment: SA-β-gal activity assay//Immunostaining
Description: β-Gal staining for cellular senescence was markedly increased in G3 TERT-null lung sections compared with control.We analyzed the levels of heterochromatin protein 1γ(HP1γ), a marker for senescence-associated heterochromatin foci, and found that immunoreActivate HP1γ was also markedly increased, with the level of HP1γin G3 TERT-/- being more than 2.5 times that in WT control animals.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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