Aging Overview

Aging gene

Gene name: MCM
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: EPC2
Gene ID: 4171
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 19001876
Experiment: Western blot
Description: All of the examined MCM family members were found downregulated as EPC2 cells underwent senescence as documented by a reduced phosphorylation level of pRB protein;the MCM2-related fragment was expressed weakly in subconfluent EPC2 cells, where subpopulation cells undergoes spontaneous senescence in primary culture.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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