| Gene name: | PDGFB |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | HDF |
| Experiment: | SA-β-gal activity assay//SAHF |
| Description: | Indeed they displayed a flattened morphology , an increase Senescence Associated β Galactosidase (SA-β-Gal) activity and an increase Senescence associated Heterochromatin Foci (SAHF). |
| Target gene: | P53 |
| Official symbol(s): | P53 |
| R-AG-Target gene: | -- |
| Subcategory: | Unclear |
| Target gene experiment: | Knockdown//SA-β-gal activity assay//SAHF |
| Target gene description: | p53 knockdown strongly decreased the appearance of the senescence population in the PDGFB expressing cells as measured by loss of the SA-β-Gal positive cells and the decreased SAHF positive cells. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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