Aging Overview

Aging gene

Gene name: NOLC1
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: 2BS
Gene ID: 9221
Category: protein coding
Phenotype: Hepatocellular carcinoma
Experimental category: HL
PMID: 28493459
Experiment: SA-β-gal activity assay//Knockdown//Cell cycle analysis
Description: NOLC1 overexpression could increase the activity of SA‐β‐gal, and knockdown of NOLC1 repressed the enhanced SA‐β‐gal activity induced by CSIG knockdown;the overexpression of NOLC1 repressed the cell proliferation and promoted cell cycle arrest in 2BS cells.


Regulatory relationship

Target gene: CSIG
Official symbol(s): RSL1D1
R-AG-Target gene: --
Subcategory: Unclear
Target gene experiment: Western blot//qRT-PCR//Knockdown
Target gene description: CSIG knockdown increased the expression of NOLC1;the overexpression of CSIG could clearly repress the expression of NOLC1.

Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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