Aging Overview

Aging gene

Gene name: NR0B2
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: CNE-1,CNE-2
Gene ID: 8431
Category: protein coding
Phenotype: Nasopharyngeal carcinoma
Experimental category: L
PMID: 26215037
Experiment: SA-β-gal activity assay//Flow cytometry//Cell morphological analysis
Description: Morphologically, CNE-2 and CNE-2-empty vector cells were vacuolated, flattened and much larger in size compared with CNE-2 SHP-1 overexpression cells.β-galactosidase staining revealed higher senescence in CNE-1 SHP-1 shRNA cells compared with CNE-1-scramble shRNA cells (23.6?±?3.4 % vs. 11.4?±?1.8 %, P?


Regulatory relationship

Target gene: P16//PRB
Official symbol(s): P16//PRB
R-AG-Target gene: Downregulation//Upregulation
Subcategory: Unclear
Target gene experiment: Western blot
Target gene description: On the other hand, compared with CNE-2-empty vector cells, CNE-2 SHP-1 overexpression cells showed decreased expression of p16 (?95 %, P?

Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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