Aging Overview

Aging gene

Gene name: CCN2
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: Human airway epithelial cell
Gene ID: 1490
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 28026993
Experiment: SA-β-gal activity assay//qRT-PCR//Cell morphological analysis
Description: CTGF overexpression markedly reduced cell growth, and this arrest in growth was associated with the cells, showing an enlarged morphology and an increase in (SA)-β-gal activity, a marker of senescence.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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