Aging Overview

Aging gene

Gene name: CKB
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: HBEC
Gene ID: 1152
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 21980054
Experiment: SA-β-gal activity assay//Western blot//Knockdown
Description: CKB knockdown concomitant with CSE exposure further increased the percentage of SA-β-gal–positive cells. We also investigated the effects of CSE exposure and CKB knockdown on p21/waf-1, a senescence-associated cyclin-dependent kinase inhibitor, by Western blotting.Both CSE and CKB knockdown induced the expression of p21/waf-1, respectively, and CKB knockdown, concomitant with CSE exposure, further induced p21/waf-1 expression.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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