Gene name: | CKB |
Aging type: | Prevent |
Aging characteristic: |
Tissue type: | -- |
Cell name: | HBEC |
Experiment: | SA-β-gal activity assay//Western blot//Knockdown |
Description: | CKB knockdown concomitant with CSE exposure further increased the percentage of SA-β-gal–positive cells. We also investigated the effects of CSE exposure and CKB knockdown on p21/waf-1, a senescence-associated cyclin-dependent kinase inhibitor, by Western blotting.Both CSE and CKB knockdown induced the expression of p21/waf-1, respectively, and CKB knockdown, concomitant with CSE exposure, further induced p21/waf-1 expression. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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