Aging Overview

Aging gene

Gene name: DICER1
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: WI-38,IMR-90
Gene ID: 23405
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 26990999
Experiment: SA-β-gal activity assay//Knockdown
Description: SiRNA‐mediated downregulation of DICER1 levels increased cellular senescence and blocked the ability of metformin to lower the number of SA‐β‐gal‐positive cells in both WI‐38 and IMR‐90 cells. Conversely, overexpression of DICER1 decreased cellular senescence.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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