Gene name: | DICER1 |
Aging type: | Prevent |
Aging characteristic: |
Tissue type: | -- |
Cell name: | WI-38,IMR-90 |
Experiment: | SA-β-gal activity assay//Knockdown |
Description: | SiRNA‐mediated downregulation of DICER1 levels increased cellular senescence and blocked the ability of metformin to lower the number of SA‐β‐gal‐positive cells in both WI‐38 and IMR‐90 cells. Conversely, overexpression of DICER1 decreased cellular senescence. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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