Gene name: | BHLHE40 |
Aging type: | Accelerate |
Aging characteristic: |
Tissue type: | -- |
Cell name: | HEK293,EC9706 |
Gene ID: | 8553 |
Category: | protein coding |
Phenotype: | Endometrial cancer |
Experimental category: | HL |
PMID: | 22844531 |
Experiment: | SA-β-gal activity assay//Colony formation assay//Western blot//Cell morphological analysis |
Description: | We transfected DEC1 into EC9706 and confirmed that overexpression of DEC1 induces senescence by SA-β-Gal staining assay and the typically enlarged and flattened cell shape. We found DEC1 overexpression significantly suppressed the growth of EC9706 and HEK293, as measured by growth rate and colony formation assay. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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