Aging Overview

Aging gene

Gene name: BHLHE40
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: HEK293,EC9706
Gene ID: 8553
Category: protein coding
Phenotype: Endometrial cancer
Experimental category: HL
PMID: 22844531
Experiment: SA-β-gal activity assay//Colony formation assay//Western blot//Cell morphological analysis
Description: We transfected DEC1 into EC9706 and confirmed that overexpression of DEC1 induces senescence by SA-β-Gal staining assay and the typically enlarged and flattened cell shape. We found DEC1 overexpression significantly suppressed the growth of EC9706 and HEK293, as measured by growth rate and colony formation assay.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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