Aging Overview

Aging gene

Gene name: BRG1
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: SW 13
Gene ID: 834543
Category: protein coding
Phenotype: Retinoblastoma
Experimental category: L
PMID: 14729964
Experiment: SA-β-gal activity assay
Description: 16.8% of the cells transfected with BRG1 were β-galactosidase positive compared to only 1.4% with the control vector.


Regulatory relationship

Target gene: P21/WAF1/SDI
Official symbol(s): P21/WAF1/SDI
R-AG-Target gene: Upregulation
Subcategory: Phosphorylation
Target gene experiment: Western blot
Target gene description: Western blotting showed that the expression of p21 was significantly down-regulated by inhibition of the BAF47 protein, while the expression level of p16 was not significantly changed in HeLa cells.

Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

Loading,please wait...