| Gene name: | SYT7 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | H23 |
| Gene ID: | 9066 |
| Category: | protein coding |
| Phenotype: | Lung cancer |
| Experimental category: | L |
| PMID: | 30647108 |
| Experiment: | SA-β-gal activity assay |
| Description: | Moreover, more beta-gal positively stained cells were found in control cells compared with SYT7 overexpressing cells, suggesting that SYT7 inhibited cellular senescence. |
| Target gene: | P16//P21//P53 |
| Official symbol(s): | P16//P21//P53 |
| R-AG-Target gene: | Downregulation//Downregulation//Downregulation |
| Subcategory: | Unclear |
| Target gene experiment: | Western blot//Knockdown//qPCR |
| Target gene description: | Knocking down the expression of SYT7 increased the mRNA levels of P16, P21 and P53, and vice versa. Consistently, Overexpression of SYT7 inhibited the protein level of P16, P21 and P53, and knocking down SYT7 increased the protein level of P16, P21 and P53. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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