Aging Overview

Aging gene

Gene name: EPAS1
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: SH-SY5Y,SKNBE2c,SKNAS
Gene ID: 2034
Category: protein coding
Phenotype: Neuroblastoma
Experimental category: HL
PMID: 26057707
Experiment: SA-β-gal activity assay//Knockdown
Description: We observed that the vehicle-treated NBL shHIF1A and shEPAS1 cells showed greater senescence compared to the vehicle-treated NBL shCTR cells. This suggested that the decreased HIF1A and EPAS1 expression in these NBL cells might make them more prone to go into senescence, independent of the ATRA treatment.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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