Gene name: | HIF1A |
Aging type: | Prevent |
Aging characteristic: |
Tissue type: | -- |
Cell name: | SH-SY5Y,SKNBE2c,SKNAS |
Gene ID: | 3091 |
Category: | protein coding |
Phenotype: | Neuroblastoma |
Experimental category: | HL |
PMID: | 26057707 |
Experiment: | SA-β-gal activity assay//Knockdown |
Description: | We observed that the vehicle-treated NBL shHIF1A and shEPAS1 cells showed greater senescence compared to the vehicle-treated NBL shCTR cells. This suggested that the decreased HIF1A and EPAS1 expression in these NBL cells might make them more prone to go into senescence, independent of the ATRA treatment. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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