| Gene name: | SIRT1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | iPSC-Ecs |
| Experiment: | SA-β-gal activity assay |
| Description: | Overexpression of SIRT1 led to a significant reduction of cells entering senescence when compared to control groups. Blocking SIRT1 with the inhibitor Ex-527 led to a higher percentage of senescent cells in all groups, suggesting a contribution of endogenous SIRT1. |
| Target gene: | -- |
| Official symbol(s): | -- |
| R-AG-Target gene: | -- |
| Subcategory: | Unclear |
| Target gene experiment: | -- |
| Target gene description: | -- |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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