| Gene name: | SREBF1 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | HDF |
| Experiment: | Knockdown//SA-β-gal activity assay//Flow cytometry |
| Description: | SREBP-1 knockdown effectively attenuated all senescence phenotypes induced by H2O2.Similar and more remarkable results by overexpressing SREBP-1 on gain of senescence phenotypes, including SA-β-galactosidase, granularity (SSC), and delayed cell growth in addition to induction of lipogenic enzymes were obtained in young HDFs. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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