Aging Overview

Aging gene

Gene name: TP53
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: HepG2
Gene ID: 7157
Category: protein coding
Phenotype: Hepatocellular carcinoma
Experimental category: L
PMID: 27980070
Experiment: MTT assay//SA-β-gal activity assay
Description: Both colony formation and cell survival were significantly reduced in the TP53+/Δ40 clones compared to the RI clones.The percentage of senescence-associated βgalactosidase (SA-β-gal)-positive cells was significantly higher in the TP53+/Δ40 clones compared to the RI clones.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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