Aging Overview

Aging gene

Gene name: ATRAID
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: ARPE?19
Gene ID: 51374
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 26934949
Experiment: SA-β-gal activity assay//LDH activity assay
Description: SA β-gal staining demonstrated that ~62.7% of cells overexpressing Apr3 were positive for SA β?gal, compared with 17.3% of the parent cells.Cell viability was then determined using an LDH activity assay and it was demonstrated cells overexpressing Apr3 exhibited decreased cell viability compared with the parent cells .Apr3 overexpression moderately inhibited cell proliferation by 34.5% compared with the parent cells as determined by a 3 [H]-thymidine incorporation assay.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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