Aging Overview

Aging gene

Gene name: CHD5
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: HepG2,Hep3B
Gene ID: 26038
Category: protein coding
Phenotype: Hepatocellular carcinoma
Experimental category: HL
PMID: 24529164
Experiment: WST-8 assay//SA-β-gal activity assay
Description: Similarly, the proliferation of Hep3B-CHD5 was lower than Hep3B-empty vector. Consistent with the lack of proliferative capacity, HepG2-CHD5 and Hep3B-CHD5 expressed senescence-associated β-galac-tosidase (SA-β-gal) activity, a marker of senescent cells. However, very few senescent cells were detected in HepG2-empty vector and Hep3B-empty vector cells.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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