Gene name: | EID3 |
Aging type: | Accelerate |
Aging characteristic: |
Tissue type: | -- |
Cell name: | MCF-7 |
Gene ID: | 493861 |
Category: | protein coding |
Phenotype: | Breast cancer |
Experimental category: | HL |
PMID: | 30114644 |
Experiment: | SA-β-gal activity assay |
Description: | Induction of EID3 expression with doxycycline augmented the effects of IR on the cells, resulting in a significant increase in the induction of SA-β-gal positive senescent cells compared to the cells exposed to IR alone without the induction of EID3 by doxycycline. |
Target gene: | P21//P57 |
Official symbol(s): | P21//P57 |
R-AG-Target gene: | Upregulation//Upregulation |
Subcategory: | Unclear |
Target gene experiment: | qRT-PCR//Western blot |
Target gene description: | The increase in p21 and p57 expression was augmented by the induction of EID3 with doxycycline. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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