Aging Overview

Aging gene

Gene name: EGFR
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: EPC2-hTERT
Gene ID: 1956
Category: protein coding
Phenotype: Endometrial cancer
Experimental category: L
PMID: 20424117
Experiment: SA-β-gal activity assay//Western blot
Description: We suspected that EGFR overexpression may trigger senescence. In fact, senescence was observed in 30–40% of EPC2-hTERT cells shortly after drug selection upon retrovirus-mediated transduction of EGFR, but not a control empty vector.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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