Aging Overview

Aging gene

Gene name: NOX4
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: MCF12A
Gene ID: 50507
Category: protein coding
Phenotype: Breast cancer
Experimental category: HL
PMID: 20523116
Experiment: SA-β-gal activity assay
Description: We performed a SA beta-galactosidase assay on the empty vector and NOX4 overexpressing cells, and determined a higher instance of senescence in the NOX4 overexpressing cell lines when compared to the empty vector controls. An increase in senescence was observed in both breast epithelial and cancer cell lines when NOX4 was overexpressed.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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