Gene name: | NOX4 |
Aging type: | Accelerate |
Aging characteristic: |
Tissue type: | -- |
Cell name: | MCF12A |
Gene ID: | 50507 |
Category: | protein coding |
Phenotype: | Breast cancer |
Experimental category: | HL |
PMID: | 20523116 |
Experiment: | SA-β-gal activity assay |
Description: | We performed a SA beta-galactosidase assay on the empty vector and NOX4 overexpressing cells, and determined a higher instance of senescence in the NOX4 overexpressing cell lines when compared to the empty vector controls. An increase in senescence was observed in both breast epithelial and cancer cell lines when NOX4 was overexpressed. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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