| Gene name: | KIR2DL4 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | NK |
| Experiment: | SA-β-gal activity assay//Cell morphological analysis//Flow cytometry |
| Description: | Primary NK cells had a characteristicflattened and enlarged morphology after activation through CD158d. The average 2D cell area of NK cells activated by CD158d was 19.5 ±11 μm2(n = 23), up from 6.6 ±2.4 μm2(n = 22)for cells stimulated with control Ab.There was an increase in senescence-associated β-galactosidase (SA-β-gal) activity, a widely used senescence biomarker.Furthermore, NK cells activated by CD158d were arrested at the G0/G1 stage of the cell cycle. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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