Aging Overview

Aging gene

Gene name: ING1
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: Fibroblast
Gene ID: 3621
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 15601862
Experiment: SA-β-gal activity assay//Cell morphological analysis
Description: Retroviral transduction with p33ING1 resulted in a change to senescence-like cell morphology, as documented by phase-contrast microscopy.We tested for expression of SA-β-Gal activity in p33ING1-infected primary human fibroblasts by use of RasV12 as a control. In accordance with the previous observations, p33ING1 induces SA-β-Gal activity to a extent similar to that seen with oncogenic Ras, suggesting that p33ING1 has potency similar to that of RasV12.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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