Gene name: | IRF5 |
Aging type: | Accelerate |
Aging characteristic: |
Tissue type: | -- |
Cell name: | MDAH087-1 |
Experiment: | SA-β-gal activity assay |
Description: | IRF5 or IRF7, induced an additional 5% senescence-associated β-gal staining over background. The combination of IRF5 with IRF7 was able to induce senescence-associated β-gal activity in 19.3% of the cells, which is equivalent to that observed in 5-aza-dC-treated immortal MDAH041 cultures. Similar results were observed in IRF5 + IRF7-overexpressing MDAH087-1 cells. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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