Aging Overview

Aging gene

Gene name: IRF5
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: MDAH087-1
Gene ID: 3663
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 18505922
Experiment: SA-β-gal activity assay
Description: IRF5 or IRF7, induced an additional 5% senescence-associated β-gal staining over background. The combination of IRF5 with IRF7 was able to induce senescence-associated β-gal activity in 19.3% of the cells, which is equivalent to that observed in 5-aza-dC-treated immortal MDAH041 cultures. Similar results were observed in IRF5 + IRF7-overexpressing MDAH087-1 cells.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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