Aging Overview

Aging gene

Gene name: CIB1
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: MCF-7
Gene ID: 10519
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 25012820
Experiment: Knockdown//SA-β-gal activity assay
Description: About 65% of KIP knockdown cells were stained intensely for senescence associated β-galactosidase (SA-β-Gal) activity and exhibited a senescent phenotype at day 15.In contrast, the growth rates of two independent KIP knockdown cells gradually slowed down and almost stopped dividing at ~5 PD.


Regulatory relationship

Target gene: TRF2
Official symbol(s): TERF2
R-AG-Target gene: --
Subcategory: Unclear
Target gene experiment: --
Target gene description: --

Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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