| Gene name: | NOX1 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | REF52,TIG-3 |
| Experiment: | SA-β-gal activity assay |
| Description: | Nox1- and Nox4- overexpressing cells ceased to proliferate and accumulated SA-β-gal during 6–7?days postinfection, whereas vector control displayed little or no senescence biomarker and growth inhibition. |
| Regulatory pathway: | P19//P38 MAPK |
| R-AG-Pathway: | Upregulation//Upregulation |
| Official symbol(s): | CDKN2D//MAKP14 |
| Pathway experiment: | Western blot |
| Pathway description: | Nox1 up‐regulated the expression of p19Arf?in REF52 cells.Moreover, a marked increase in the level of phosphorylated p38MAPK was detected in Nox1‐ or Nox4‐expressing cells . |
Annotation:
Loading,please wait...