Gene name: | NOX4 |
Aging type: | Prevent |
Aging characteristic: |
Tissue type: | -- |
Cell name: | VSMC |
Experiment: | SA-β-gal activity assay//BrdU assay |
Description: | The number of SA-β-gal-positive cells correlated inversely with the level of NOX4 expression obtained after transfection with different siRNA sequences.Moreover, cells with diminished NOX4 expression cease to proliferate since a significant decrease in the number of cells able to replicate DNA was observed already 3 days after transfection. These cells did not restart DNA replication during the next 4 days of the culture. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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