| Gene name: | PEBP1 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | A549 |
| Experiment: | SA-β-gal activity assay//Western blot |
| Description: | Elimination of RKIP could increase ERK activation and suppress the cellular senescence. |
| Target gene: | P53 |
| Official symbol(s): | P53 |
| R-AG-Target gene: | -- |
| Subcategory: | Unclear |
| Target gene experiment: | CHIP |
| Target gene description: | Moreover, RKIP was a direct target of p53. |
| Regulatory pathway: | RAF-MAPK |
| R-AG-Pathway: | Downregulation |
| Official symbol(s): | ZHX2-MAPK |
| Pathway experiment: | SA-β-gal activity assay//Western blot |
| Pathway description: | Elimination of RKIP could increase ERK activation and suppress the cellular senescence. In contrast, suppression of Ras-Raf-ERK pathway using Raf kinase inhibitor could induce the cellular senescence . |
Annotation:
Loading,please wait...