| Gene name: | CHUK |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | Tumor tissue |
| Cell name: | -- |
| Gene ID: | 1147 |
| Category: | protein coding |
| Phenotype: | Lung cancer |
| Experimental category: | HL |
| PMID: | 29311298 |
| Experiment: | SA-β-gal activity assay//Ki67 staining |
| Description: | KrasG12D;IkkαΔLu lung ADCs displayed substantially less SA-β-gal staining and more Ki67 than KrasG12D ADCs. |
| Regulatory pathway: | NRF2-NQO1 |
| R-AG-Pathway: | Downregulation |
| Official symbol(s): | NFE2L2-NQO1 |
| Pathway experiment: | SA-β-gal activity assay//Western blot |
| Pathway description: | Indeed, KrasIKKαL cells expressed reduced IKKα, NRF2, NQO1, p53, and p21 and showed attenuated cell senescence compared with Kras-CL cells. |
Annotation:
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