Gene name: | DUSP1 |
Aging type: | Accelerate |
Aging characteristic: |
Tissue type: | -- |
Cell name: | SO-Rb5 |
Experiment: | SA-β-gal activity assay//Knockdown |
Description: | DUSP1 plasmid and siRNA transfection enhanced and attenuated SO-Rb5 cell senescence induced by AGII, respectively, revealing that DUSP1 participated in SO-Rb5 cell senescence induced by AGII. |
Regulatory pathway: | AKT |
R-AG-Pathway: | Downregulation |
Official symbol(s): | AKT1 |
Pathway experiment: | Western blot |
Pathway description: | DUSP1 plasmid and siRNA transfection inhibited and strengthened Akt signaling in SO-Rb5 cell senescence induced by AGII, respectively, revealing that DUSP1 participated in SO-Rb5 cell senescence induced by AGII. |
Annotation:
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