| Gene name: | FOXM1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | H929 |
| Gene ID: | 2305 |
| Category: | protein coding |
| Phenotype: | Multiple myeloma |
| Experimental category: | HL |
| PMID: | 30463534 |
| Experiment: | SA-β-gal activity assay//Knockdown |
| Description: | Left shows that FOXM1 knockdown sufficed to induce β-gal activity in myeloma. |
| Target gene: | RB |
| Official symbol(s): | RB |
| R-AG-Target gene: | Downregulation |
| Subcategory: | Unclear |
| Target gene experiment: | Western blot |
| Target gene description: | Densitometric analysis of Western blots showed that total Rb and phosphorylated Rb (pRb) were increased in FOXM1Hi cells by 20-40%, with somewhat higher levels seen in XG1 than CAG cells. Conversely, Rb and pRb were decreased in FOXM1Lo cells (~ 30 to 50%), with the loss of the latter somewhat exceeding that of the former. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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