Aging Overview

Aging gene

Gene name: NBS1
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: MCF-7
Gene ID: 821254
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 24141789
Experiment: Crystal violet assay//SA-β-gal activity assay
Description: Like FOXM1, NBS1-knockdown sensitized MCF-7 and MCF-7EpiRcells to long-term proliferative arrest following treatment with epirubicin. Consistently, NBS1 knockdown in MCF-7 and MCF-7EpiRcells also enhanced the number of cells exhibiting SA-β-gal activity and morphology at 0 and 10nM epirubicin.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

Loading,please wait...