Aging Overview

Aging gene

Gene name: TBX2
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: WI-38
Gene ID: 6909
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 22002537
Experiment: SA-β-gal activity assay//Immunostaining
Description: Additionally, TBX2/PML-IV-expressing cells stained positive for Ki67 and negative for SA-β-Gal when compared with DON/PML-IV cells.


Regulatory relationship

Target gene: PML
Official symbol(s): PML
R-AG-Target gene: Downregulation
Subcategory: Unclear
Target gene experiment: qRT-PCR//Western blot
Target gene description: We detected a robust increase both in TBX2 transcript (~4-fold) and in protein levels (B3-fold) in PML-/- MEFs when compared with PML+/+ MEFs as determined by qRT-PCR (left panel) and western blot analysis (right panel).

Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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